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nmr spectroscopy  (Bruker Corporation)


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    Bruker Corporation nmr spectroscopy
    Nmr Spectroscopy, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 99/100, based on 11001 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nmr spectroscopy/product/Bruker Corporation
    Average 99 stars, based on 11001 article reviews
    nmr spectroscopy - by Bioz Stars, 2026-05
    99/100 stars

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    Leveraging phenotypic and hospitalization data from UK Biobank, this study investigated the prospective and causal association of physical frailty and its components with MASLD incidence, as well as the multiplicative and additive interactions with covariates. Then, capitalizing on high-throughput metabolomics data, we conducted a metabolome-wide association analysis to identify frailty-associated metabolites and dissect their role in mediating MASLD risk. Last, we reran the above analyses using MRI-derived PDFF as a secondary outcome and validated the association analysis on matched data using a propensity score matching procedure. Icons were made from www.svgrepo.com/ .

    Journal: Science Advances

    Article Title: The metabolomic signatures mediate associations between physical frailty and metabolic dysfunction–associated steatotic liver disease

    doi: 10.1126/sciadv.aeg4939

    Figure Lengend Snippet: Leveraging phenotypic and hospitalization data from UK Biobank, this study investigated the prospective and causal association of physical frailty and its components with MASLD incidence, as well as the multiplicative and additive interactions with covariates. Then, capitalizing on high-throughput metabolomics data, we conducted a metabolome-wide association analysis to identify frailty-associated metabolites and dissect their role in mediating MASLD risk. Last, we reran the above analyses using MRI-derived PDFF as a secondary outcome and validated the association analysis on matched data using a propensity score matching procedure. Icons were made from www.svgrepo.com/ .

    Article Snippet: Metabolomic analysis was performed on baseline EDTA plasma samples from a randomly selected subset of participants using a high-throughput NMR spectroscopy platform provided by Nightingale Health Ltd. ( ).

    Techniques: High Throughput Screening Assay, Derivative Assay